JOURNAL ARTICLE
REVIEW

Drug Burden Index in older adults: theoretical and practical issues

Lisa Kouladjian, Danijela Gnjidic, Timothy F Chen, Arduino A Mangoni, Sarah N Hilmer
Clinical Interventions in Aging 2014, 9: 1503-15
25246778
Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative review discusses the research and clinical applications of the Drug Burden Index, and its advantages and limitations, compared with other pharmacologically developed measures of high-risk prescribing.

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