Create a free QxMD account to take advantage of the features offered by Read like saving your papers and creating collections.

Get Started

JOURNAL ARTICLE

REVIEW

Drug Burden Index in older adults: theoretical and practical issues

Lisa Kouladjian, Danijela Gnjidic, Timothy F Chen, Arduino A Mangoni, Sarah N Hilmer

Clinical Interventions in Aging 2014, 9: 1503-15

Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative review discusses the research and clinical applications of the Drug Burden Index, and its advantages and limitations, compared with other pharmacologically developed measures of high-risk prescribing.

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Physical and cognitive performance and burden of anticholinergics, sedatives, and ACE inhibitors in older women. Y-J Cao, D E Mager, E M Simonsick, S N Hilmer, S M Ling, B G Windham, V Crentsil, S Yasar, L P Fried, D R Abernethy Clinical Pharmacology and Therapeutics 2008, 83 (3): 422-9

Effect of polypharmacy, potentially inappropriate medications and anticholinergic burden on clinical outcomes: a retrospective cohort study. Wan-Hsuan Lu, Yu-Wen Wen, Liang-Kung Chen, Fei-Yuan Hsiao CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne 2015 March 3, 187 (4): E130-E137

A drug burden index to define the functional burden of medications in older people. Sarah N Hilmer, Donald E Mager, Eleanor M Simonsick, Ying Cao, Shari M Ling, B Gwen Windham, Tamara B Harris, Joseph T Hanlon, Susan M Rubin, Ronald I Shorr, Douglas C Bauer, Darrell R Abernethy Archives of Internal Medicine 2007 April 23, 167 (8): 781-7

Associations of drug burden index with falls, general practitioner visits, and mortality in older people. Prasad S Nishtala, Sujita W Narayan, Ting Wang, Sarah N Hilmer Pharmacoepidemiology and Drug Safety 2014, 23 (7): 753-8

Associations between drug burden index and falls in older people in residential aged care. Nicholas M Wilson, Sarah N Hilmer, Lyn M March, Ian D Cameron, Stephen R Lord, Markus J Seibel, Rebecca S Mason, Jian Shen Chen, Robert G Cumming, Philip N Sambrook Journal of the American Geriatrics Society 2011, 59 (5): 875-80

Drug burden index and beers criteria: impact on functional outcomes in older people living in self-care retirement villages. Danijela Gnjidic, David G Le Couteur, Darrell R Abernethy, Sarah N Hilmer Journal of Clinical Pharmacology 2012, 52 (2): 258-65

Effects of drug burden index on cognitive function in older men. Danijela Gnjidic, David G Le Couteur, Vasi Naganathan, Robert G Cumming, Helen Creasey, Louise M Waite, Anita Sharma, Fiona M Blyth, Sarah N Hilmer Journal of Clinical Psychopharmacology 2012, 32 (2): 273-7

Drug Burden Index and hospitalization among community-dwelling older people. Eija Lönnroos, Danijela Gnjidic, Sarah N Hilmer, J Simon Bell, Hannu Kautiainen, Raimo Sulkava, Sirpa Hartikainen Drugs & Aging 2012 May 1, 29 (5): 395-404

Investigating polypharmacy and drug burden index in hospitalised older people. O Best, D Gnjidic, S N Hilmer, V Naganathan, A J McLachlan Internal Medicine Journal 2013, 43 (8): 912-8

Anticholinergic and sedative medicines - prescribing considerations for people with dementia. J Simon Bell, Carmel Mezrani, Natalie Blacker, Tammy LeBlanc, Oliver Frank, Christopher P Alderman, Simone Rossi, Debra Rowett, Russell Shute Australian Family Physician 2012, 41 (1-2): 45-9

Make the most of Read.
Download the mobile app.

Want full text access to this paper?

Use Read by QxMD to access full text via your institution or open access sources.

Read also provides personalized recommendations to keep you up to date in your field.

Existing User

New to Read

Drug Burden Index in older adults: theoretical and practical issues

Discussion

Related Papers

Want full text access to this paper?

Save your favorite articles in one place with a free QxMD account.

Read

Search Tips