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Successful treatment of Kimura's disease with leflunomide and methylprednisolone: a case report

Xiao-Rong Ma, Shu-Jia Xin, Tian-Xiang Ouyang, Yue-Ting Ma, Wei-Ying Chen, Meng-Ling Chang
International Journal of Clinical and Experimental Medicine 2014, 7 (8): 2219-22
Kimura's disease (KD) is an uncommon, chronic inflammatory disease characterized by tumor-like lesions in the soft tissue and lymph nodes and increased peripheral blood eosinophil counts and serum immunoglobulin E (IgE). Prednisone is widely used to treat the disease. Here, we reported a 59-year-old KD patient failed to response to prednisone. Leflunomide combined with methylprednisolone (Medrol) were carried out to treat KD and encouraging outcome was obtained during the medication and 1 year follow up period.

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