Orthodontic treatment for a patient with hereditary angiodema: a case report

Kate Waldon, Sophy Kathleen Barber, Richard James Spencer
International Journal of Paediatric Dentistry 2015, 25 (3): 229-32

BACKGROUND: Hereditary angiodema (HAE), also known as C1 esterase inhibitor deficiency, causes sufferers to experience episodic subcutaneous and submucosal oedema. These episodes can be triggered by dental treatment and manifest as life-threatening oedematous swelling in the head and neck region.

CASE REPORT: This case report reviews an adolescent with hereditary angiodema whose malocclusion required orthodontic intervention. Due to her complex and unpredictable reaction to dental treatment, various options were explored before determining the appropriate care pathway for this patient. Trial placement of a sectional fixed appliance tested the tissue reaction prior to comprehensive treatment including extractions and fixed orthodontic appliances.

CONCLUSION: This report demonstrates successful interdisciplinary management facilitating orthodontic care in a patient with HAE.

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