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A critical role for natural killer cells in dendritic cell-based anticancer immunotherapy.
Oncoimmunology 2014
Multipronged immunotherapies that activate both T cells and natural killer (NK) cells may result in more robust and durable anticancer responses. The successful outcome of dendritic cell (DC)-based vaccination therapy involves a hitherto unrecognized role for NK cells. Combinatorial regimens that enhance the contribution of NK cells to the anticancer immune response may therefore improve clinical outcomes.
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