Endometrial cancer: a review and current management strategies: part I

William M Burke, James Orr, Mario Leitao, Emery Salom, Paola Gehrig, Alexander B Olawaiye, Molly Brewer, Dave Boruta, Jeannine Villella, Tom Herzog, Fadi Abu Shahin
Gynecologic Oncology 2014, 134 (2): 385-92
Endometrial carcinoma is the most common gynecologic malignancy. A thorough understanding of the epidemiology, pathophysiology, and management strategies for this cancer allows the obstetrician-gynecologist to identify women at increased risk, contribute toward risk reduction, and facilitate early diagnosis. The Society of Gynecologic Oncology's Clinical Practice Committee has reviewed the literature and created evidence-based practice recommendations for diagnosis and treatment. This article examines: • Risk factors, including genetic predisposition • Diagnostic and metastatic evaluation • Surgical management of early and advanced cancer, including lymphadenectomy in early cancer.

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