MENU ▼
Read by QxMD icon Read
search
OPEN IN READ APP
JOURNAL ARTICLE

Predictive value of gelsolin for the outcomes of preterm neonates: a pilot study

Mehmet Kose, Tuba Elmas, Selma Gokahmetoglu, Mehmet Adnan Ozturk, Duygu Ekinci, Ferhan Elmali, Hulya Halis, Osman Bastug
Pediatrics International: Official Journal of the Japan Pediatric Society 2014, 56 (6): 856-859
24862494

BACKGROUND: Plasma gelsolin is a circulating actin-binding protein that has a protective role against tissue injuries. Our aim was to compare the baseline levels of gelsolin in premature infants with neonatal outcomes.

METHODS: A total of 32 preterm neonates born at 23-32 weeks of gestation were enrolled in the study.

RESULTS: Plasma gelsolin levels at 72 h were significantly lower in patients with respiratory distress syndrome, in patients who were administered surfactant therapy and in patients who developed sepsis (P < 0.05). Plasma gelsolin levels at 28 days were significantly lower in patients who developed bronchopulmonary dysplasia and retinopathy of prematurity (P < 0.05).

CONCLUSIONS: Low plasma gelsolin levels in the first postnatal month may be associated with poor outcomes in premature infants.

Comments

You need to log in or sign up for an account to be able to comment.

No comments yet, be the first to post one!

Related Papers

Available on the App Store

Available on the Play Store
Remove bar
Read by QxMD icon Read
24862494
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"