Association of lichen planopilaris with thyroid disease: a retrospective case-control study

Natasha Atanaskova Mesinkovska, Nikoleta Brankov, Melissa Piliang, Angela Kyei, Wilma F Bergfeld
Journal of the American Academy of Dermatology 2014, 70 (5): 889-92

BACKGROUND: Studies on the precise causes and comorbidities seen with lichen planopilaris (LPP) are limited.

OBJECTIVE: We sought to determine the prevalence of thyroid diseases in patients with LPP.

METHODS: Medical records of 166 patients with LPP and 81 age- and gender-matched control subjects seen in the Department of Dermatology at the Cleveland Clinic Foundation in Ohio between 2000 and 2013 were reviewed.

RESULTS: A diagnosis of thyroid disease was present in 34% (n = 57) of the 166 patients with LPP, and in 11% (n = 9) of the control subjects (P = .0001). When confined to hypothyroidism only, this disease was found in 29% (n = 48) of the patients with LPP and 9% (n = 7) of the control subjects (P = .0003).

LIMITATIONS: This study was limited by being retrospective.

CONCLUSION: In our patients, LPP was associated with thyroid disease, especially hypothyroidism.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"