Photoacoustic guided ultrasound wavefront shaping for targeted acousto-optic imaging

Jacob Staley, Erwin Hondebrink, Wilma Peterson, Wiendelt Steenbergen
Optics Express 2013 December 16, 21 (25): 30553-62
To overcome speed of sound aberrations that negatively impact the acoustic focus in acousto-optic imaging, received photoacoustic signals are used to guide the formation of ultrasound wavefronts to compensate for acoustic inhomogeneities. Photoacoustic point sources composed of gold and superparamagnetic iron oxide nanoparticles are used to generate acoustic waves that acoustically probe the medium as they propagate to the detector. By utilizing cross-correlation techniques with the received photoacoustic signal, transmitted ultrasound wavefronts compensate for the aberration, allowing for optimized and configurable ultrasound transmission to targeted locations. It is demonstrated that utilizing a portable commercially available ultrasound system using customized software, photoacoustic guided ultrasound wavefront shaping for targeted acousto-optic imaging is robust in the presence of large, highly attenuating acoustic aberration.


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Available on the App Store

Available on the Play Store
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"