Comparison of the long-term results of Roux-en-Y gastric bypass and sleeve gastrectomy for morbid obesity: a systematic review and meta-analysis of randomized and nonrandomized trials.

PURPOSE: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are 2 of the most widely used bariatric procedures today, in this meta-analysis, both techniques were compared for evaluating the efficacy and safety of the treatment of morbid obesity.

MATERIALS AND METHODS: Systematic literature search of Cochrane Controlled Trials Register Databases, Medline, Embase, ISI databases, and Chinese Biomedical Literature Database was performed. Statistical analyses were carried out using RevMan software.

RESULTS: Thirty-two recent studies including 6526 patients in total were included in this meta-analysis. Compared with SG, RYGB had significantly better effect in resolving type 2 diabetes mellitus, hypertension, hypercholesterolemia, gastroesophageal reflux disease, and arthritis. However, RYGB had higher incidence of complications and reoperation, and longer operation time than SG.

CONCLUSIONS: RYGB was more effective than SG in the resolution of obesity-related comorbidities, SG was a safer procedure with a reduced rate of complications and reoperation.