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Adrenocortical carcinoma.

Tobias Else, Alex C Kim, Aaron Sabolch, Victoria M Raymond, Asha Kandathil, Elaine M Caoili, Shruti Jolly, Barbra S Miller, Thomas J Giordano, Gary D Hammer
Endocrine Reviews 2014 April
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy, often with an unfavorable prognosis. Here we summarize the knowledge about diagnosis, epidemiology, pathophysiology, and therapy of ACC. Over recent years, multidisciplinary clinics have formed and the first international treatment trials have been conducted. This review focuses on evidence gained from recent basic science and clinical research and provides perspectives from the experience of a large multidisciplinary clinic dedicated to the care of patients with ACC.

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