[Weber-Christian disease].

In pursuance of the Federal law "On the fundamentals of health protection in RF", the Russian Ministry of Health approved the list of so-called orphan diseases, i.e. rare pathologies of great medical and social significance due to their life-threatening nature and immense burden on health budget. Weber-Christian disease is a chronic recurrent orphan diseases characterized by formation of painful dense nodes in subcutaneous fat free from suppuration and accompanied by episodic temperature changes, chill, muscular pain and sometimes damage to internal organs. The disease recurs at irregular intervals.