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ENGLISH ABSTRACT
JOURNAL ARTICLE
[Evolutionary and transmission characteristics of rabies viruses in Asia].
OBJECTIVE: To understand the rabies virus (RABV) evolutionary relationship between the strains of China and Asia and to know the evolution and transmission characteristics of RABV in Asia.
METHODS: The G sequences of representative strains from China were selected and combined the sequences of other countries in Asia to analyze using BEAST and MigraPhyla software.
RESULTS: The phylogenetic analysis showed that six groups (China I-VI) of China had different epidemic range: China I , II and V groups just cycled in our country; China VI group, from Guangxi and Yunnan provinces, crossed with Southeast Asian strains; China III group and IV group also have closer genetic relationship with Asian country strains.
CONCLUSION: Geographic migration in Asia showed that Thailand and India may be two rabies transmission centers in Asia.
METHODS: The G sequences of representative strains from China were selected and combined the sequences of other countries in Asia to analyze using BEAST and MigraPhyla software.
RESULTS: The phylogenetic analysis showed that six groups (China I-VI) of China had different epidemic range: China I , II and V groups just cycled in our country; China VI group, from Guangxi and Yunnan provinces, crossed with Southeast Asian strains; China III group and IV group also have closer genetic relationship with Asian country strains.
CONCLUSION: Geographic migration in Asia showed that Thailand and India may be two rabies transmission centers in Asia.
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