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Lack of MERS coronavirus neutralizing antibodies in humans, eastern province, Saudi Arabia.

Stefanie Gierer, Heike Hofmann-Winkler, Waleed H Albuali, Stephanie Bertram, Abdullah M Al-Rubaish, Abdullah A Yousef, Awatif N Al-Nafaie, Amein K Al-Ali, Obeid E Obeid, Khaled R Alkharsah, Stefan Pöhlmann
Emerging Infectious Diseases 2013 December
We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.

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