Isolated posterior fossa involvement in posterior reversible encephalopathy syndrome

Yukie Shimizu, Khin Khin Tha, Akihiro Iguchi, Yuko Cho, Atsushi Yoshida, Noriyuki Fujima, Akiko Tsukahara, Hiroki Shirato, Satoshi Terae
Neuroradiology Journal 2013, 26 (5): 514-9
Posterior reversible encephalopathy syndrome (PRES) is characterized by reversible vasogenic edema affecting the subcortical white matter of bilateral occipital and parietal lobes. We describe a case of isolated posterior fossa involvement of PRES which occurred during remission induction chemotherapy for T-cell acute lymphoblastic leukemia. Both the brainstem and cerebellum were extensively involved, but the supratentorial structures were completely spared. The follow-up magnetic resonance images revealed reversibility of most lesions. The knowledge of atypical radiological features of PRES is essential for prompt diagnosis.

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