COMMENT
JOURNAL ARTICLE
Add like
Add dislike
Add to saved papers

That chorioamnionitis is a risk factor for bronchopulmonary dysplasia--the case against.

Bronchopulmonary dysplasia (BPD) is the most frequent long term sequelae in infants born at less than 29 weeks of gestational age (GA) and histological chorioamnionitis (CA) is the most frequent condition associated with very preterm birth. Numerous studies have explored the association between BPD and CA with conflicting results. This inconsistency may be attributable to differences in populations, definitions, methods, and whether potential confounding factors such as GA, antenatal steroids, and post natal events were considered. A recent systematic review and meta-analysis shows some evidence of an association between BPD and CA; however, results adjusting for important confounders show more conservative measures of association. In addition, there was evidence of publication bias: when controlling for publication bias the results were more conservative and adjusted results were no longer significant. Recent large cohort studies not included in the systematic review do not support the belief that CA is associated with an increased risk of BPD. Despite a large body of evidence, CA cannot be definitively considered a risk factor for BPD.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app