[Cardiac sympathetic innervation imaging with myocardial MIBG scintigraphy]

Eugenio Annibale Genovese, Vania Mallardo, Stefania Cipullo, Antonino Restuccia, Domenico Galea, Gianfranco D'Agosto, Imma Di Lanno, Salvatore Cappabianca
Recenti Progressi in Medicina 2013, 104 (7-8): 356-60
Metaiodobenzylguanidine (MIBG) was developed initially as a tracer for oncological imaging; when labeled with 123 I or 131 I, it may detect APUDomas, such as pheochromocytomas and paragangliomas. In the last years, MIBG has found an important role also in neurology and cardiology, as cardiac innervation tracer. Actually, MIBG cardiac imaging is a universally accepted method to estimate cardiac sympathetic innervations. This review covers the role of MIBG cardiac imaging in Parkinson disease and parkinsonisms, from the pathophysiological premises for cardiac denervation to new emerging data.

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