Periodontitis may be associated with chronic kidney disease, but current evidence is insufficient

Wenche S Borgnakke
Journal of Evidence-based Dental Practice 2013, 13 (3): 88-90

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Periodontitis and chronic kidney disease: a systematic review of the association of diseases and the effect of periodontal treatment on estimated glomerular filtration rate. Chambrone L, Foz AM, Guglielmetti RM, Pannuti CM, Artese HP, Feres M, Romito GA. J Clin Periodontol 2013;40(5):443-56.

REVIEWER: Wenche S. Borgnakke, DDS, MPH, PhD PURPOSE/QUESTION: The authors conducted systematic reviews to try to answer the following two questions: Q1) Is periodontitis a risk factor for chronic kidney disease (CKD)? and Q2) Can periodontal treatment improve the estimated glomerular filtration rate (eGFR) of patients with periodontitis?

SOURCE OF FUNDING: No external support was received

TYPE OF STUDY/DESIGN: Q1) Systematic review with meta-analysis of data; Q2) Systematic review

LEVEL OF EVIDENCE: Level 2: Limited-quality, patient-oriented evidence

STRENGTH OF RECOMMENDATION GRADE: Grade C: Consensus, disease-oriented evidence, usual practice, expert opinion, or case series for studies of diagnosis, treatment, prevention, or screening.

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