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Journal Article
Research Support, Non-U.S. Gov't
Low-dose chest computed tomography with sinogram-affirmed iterative reconstruction, iterative reconstruction in image space, and filtered back projection: studies on image quality.
Journal of Computer Assisted Tomography 2013 July
OBJECTIVE: This study aimed to determine optimal strength of sinogram-affirmed iterative reconstruction (SAFIRE) and to evaluate image quality (IQ) of low-dose chest computed tomography (LDCT) using SAFIRE compared with iterative reconstruction in image space (IRIS) and filtered back projection (FBP).
METHODS: Thirty patients underwent LDCT. Computed tomography (CT) was reconstructed using 5 strengths of SAFIRE (S1-S5), IRIS, and FBP. Objective noise of CT was measured. Two radiologists evaluated CT for subjective IQ, beam-hardening artifacts, and overall IQ.
RESULTS: Measured noise was highest in FBP, followed by S1, S2, S3, IRIS, S4, and S5. S2 and S3 demonstrated significantly higher overall IQ scores than the other strengths (P < 0.05). Overall IQ and beam-hardening artifacts of S2 and S3 were significantly better than those in FBP and IRIS (P < 0.001).
CONCLUSIONS: S2 or S3 strengths of SAFIRE can be used practically in clinical routines and may have more potential than IRIS and FBP for LDCT with improved IQ.
METHODS: Thirty patients underwent LDCT. Computed tomography (CT) was reconstructed using 5 strengths of SAFIRE (S1-S5), IRIS, and FBP. Objective noise of CT was measured. Two radiologists evaluated CT for subjective IQ, beam-hardening artifacts, and overall IQ.
RESULTS: Measured noise was highest in FBP, followed by S1, S2, S3, IRIS, S4, and S5. S2 and S3 demonstrated significantly higher overall IQ scores than the other strengths (P < 0.05). Overall IQ and beam-hardening artifacts of S2 and S3 were significantly better than those in FBP and IRIS (P < 0.001).
CONCLUSIONS: S2 or S3 strengths of SAFIRE can be used practically in clinical routines and may have more potential than IRIS and FBP for LDCT with improved IQ.
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