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A single histrelin implant is effective for 2 years for treatment of central precocious puberty.

Katherine A Lewis, Andrea K Goldyn, Karen W West, Erica A Eugster
Journal of Pediatrics 2013 October
We investigated whether a "yearly" histrelin implant would provide pubertal suppression when left in place for 2 years. Equivalent suppression was observed when comparing 12 and 24 months in 33 children with central precocious puberty. A single implant for 2 years reduces cost and number of implant procedures.

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