We have located links that may give you full text access.
English Abstract
Journal Article
[Analysis of Y chromosome microdeletion in non-obstructive male infertile patients with azoospermia and severe oligozoospermia].
Sichuan da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition 2013 March
OBJECTIVE: To investigate the frequency and types of the major Y chromosome microdeletions in non-obstructive infertile males with azoospermia and severe oligozoospermia in Chinese.
METHODS: Multiplex polymerise chain reaction (PCR) amplification was used to detect Y chromosome microdeletion in 203 nonobstructive infertile men, including 125 patients with azoospermia and 78 with severe oligozoospermia, as well as 100 fertile men in the control group.
RESULTS: Among the 203 non-obstructive infertile cases, 22 (10.8%) carried a Y chromosome microdeletion and the frequencies of such microdeletions were 9.6% in azoospermia and 12.8% in oligozoospermia. The most frequent microdeletions were in the AZFc, and all the severe oligospermia were found microdeletions in the AZFc. No Y chromosome microdeletion was detected in the control group.
CONCLUSION: It is necessary to offer genetic screening and counseling to infertility men prior to intracytoplasmic sperm injection (ICSI) or in-vitro fertilization (IVF).
METHODS: Multiplex polymerise chain reaction (PCR) amplification was used to detect Y chromosome microdeletion in 203 nonobstructive infertile men, including 125 patients with azoospermia and 78 with severe oligozoospermia, as well as 100 fertile men in the control group.
RESULTS: Among the 203 non-obstructive infertile cases, 22 (10.8%) carried a Y chromosome microdeletion and the frequencies of such microdeletions were 9.6% in azoospermia and 12.8% in oligozoospermia. The most frequent microdeletions were in the AZFc, and all the severe oligospermia were found microdeletions in the AZFc. No Y chromosome microdeletion was detected in the control group.
CONCLUSION: It is necessary to offer genetic screening and counseling to infertility men prior to intracytoplasmic sperm injection (ICSI) or in-vitro fertilization (IVF).
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app