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Phase-sensitive swept-source optical coherence tomography imaging of the human retina with a vertical cavity surface-emitting laser light source

WooJhon Choi, Benjamin Potsaid, Vijaysekhar Jayaraman, Bernhard Baumann, Ireneusz Grulkowski, Jonathan J Liu, Chen D Lu, Alex E Cable, David Huang, Jay S Duker, James G Fujimoto
Optics Letters 2013 February 1, 38 (3): 338-40
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Despite the challenges in achieving high phase stability, Doppler swept-source/Fourier-domain optical coherence tomography (OCT) has advantages of less fringe washout and faster imaging speeds compared to spectral/Fourier-domain detection. This Letter demonstrates swept-source OCT with a vertical cavity surface-emitting laser light source at 400 kHz sweep rate for phase-sensitive Doppler imaging, measuring pulsatile total retinal blood flow with high sensitivity and phase stability. A robust, simple, and computationally efficient phase stabilization approach for phase-sensitive swept-source imaging is also presented.

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