JOURNAL ARTICLE

A fluorescent ratiometric chemodosimeter for Cu2+ based on TBET and its application in living cells

Jiangli Fan, Peng Zhan, Mingming Hu, Wen Sun, Jizhou Tang, Jingyun Wang, Shiguo Sun, Fengling Song, Xiaojun Peng
Organic Letters 2013 February 1, 15 (3): 492-5
23339382
Based on a through bond energy transfer (TBET) between Rhodamine and a naphthalimide fluorophore, a fluorescent ratiometric chemodosimeter RN1 was designed and prepared for single selective detection of Cu(2+) in aqueous solution and in living cells, as Cu(2+) acts as not only a selective recognizing guest but also a hydrolytic promoter.

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