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JOURNAL ARTICLE

Common bile duct adenocarcinoma in a patient with situs inversus totalis: report of a rare case

Hafida Benhammane, Saoussane Kharmoum, Sylvain Terraz, Thierry Berney, Thai Nguyen-Tang, Muriel Genevay, Omar El Mesbahi, Arnaud Roth
BMC Research Notes 2012 December 12, 5: 681
23234596

BACKGROUND: Situs inversus totalis represents an unusual anomaly characterized by a mirror-image transposition of the abdominal and thoracic viscera. It often occurs concomitantly with other disorders that make difficult diagnosis and management of abdominal pathology. The relationship between situs inversus totalis and cancer remains unclear.

CASE PRESENTATION: We describe a 33-year old Guinean man with situs inversus totalis who presented with obstructive jaundice. Imaging and endoscopic modalities demonstrated a mass of distal common bile duct which biopsy identified an adenocarcinoma. The patient was successfully treated by cephalic pancreaticoduodenectomy followed by adjuvant chemoradiation and he is doing well without recurrence 8 months after surgery.

CONCLUSION: The occurrence of bile duct adenocarcinoma in patient with situs inversus totalis accounts as a rare coincidence. In this setting, when the tumor is resectable, surgical management should be considered without contraindication and must be preceded by a careful preoperative staging.

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