Clostridium carboxidivorans strain P7T recombinant formate dehydrogenase catalyzes reduction of CO(2) to formate

Apostolos Alissandratos, Hye-Kyung Kim, Hayden Matthews, James E Hennessy, Amy Philbrook, Christopher J Easton
Applied and Environmental Microbiology 2013, 79 (2): 741-4
Recombinant formate dehydrogenase from the acetogen Clostridium carboxidivorans strain P7(T), expressed in Escherichia coli, shows particular activity towards NADH-dependent carbon dioxide reduction to formate due to the relative binding affinities of the substrates and products. The enzyme retains activity over 2 days at 4°C under oxic conditions.

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