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The zebrafish as a model for paediatric diseases.
Acta Paediatrica 2013 Februrary
UNLABELLED: The rapid increase in information about genes and their associations with human diseases has highlighted the need for model organisms suitable for genetic manipulation and drug testing. The zebrafish is a valuable vertebrate animal model that offers many advantages, including the relative ease of husbandry and genetic manipulation and the capacity for high-throughput screens. In this review, we describe the zebrafish as a model for paediatric diseases, with particular emphasis on haematopoietic and infectious diseases.
CONCLUSION: The zebrafish has become an established vertebrate model in which to elucidate the molecular mechanisms of various human diseases.
CONCLUSION: The zebrafish has become an established vertebrate model in which to elucidate the molecular mechanisms of various human diseases.
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