COMPARATIVE STUDY
JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Add like
Add dislike
Add to saved papers

Biological activity assessment and phenolic compounds characterization from the fruit pericarp of Litchi chinensis for cosmetic applications.

CONTEXT: Litchi chinensis Sonn. (Spindaceae) is an important economic fruit of Thailand. Therapeutic effects of the fruits are contributed by anti-inflammatory phenolics.

OBJECTIVE: To extract the litchi fruit pericarp in order to identify biologically actives substances with potential for cosmetic application.

MATERIALS AND METHODS: The litchi pericarp was macerated by 70% ethanol (EtOH) and partitioned using n-hexane and ethyl acetate (EtOAc). In vitro antioxidant activities were assessed by 1, 1-diphenyl-2-picrylhydrazyl (DPPH), ABTS and ferric reducing ability of plasma (FRAP) assays including tyrosinase inhibitory effect. Cellular radical scavenging capacity was monitored in a normal human fibroblast cell culture (NHF). Total phenolic content was determined and characterized by HPLC.

RESULTS: The EtOAc fraction was a significant antioxidant, stronger than ascorbic acid (p < 0.01), as assessed by ABTS (IC(50) = 7.137 ± 0.021 μg/mL), DPPH (IC(50) = 2.288 ± 0.063 μg/mL) and FRAP (EC(1mMFeSO4) = 8013.183 ± 58.804 μg/mL) assays. It demonstrated an antityrosinase effect (IC(50) = 197.860 ± 1.230 μg/mL) and showed no cytotoxic activity toward Vero and NHF cells, at a maximum tested concentration (50 μg/mL), with cellular antioxidant activity. Total phenolic content was highest in the most potent antioxidant fraction. Quercetin, rosmarinic and gallic acids were found. Total phenolic content is highly related to FRAP, antityrosinase, and ABTS activities.

DISCUSSION AND CONCLUSION: Pericarp from litchi fruit can be obtained abundantly from agricultural waste, and the strong antioxidant activity demonstrated in this report may have application in topical cosmetic products. This ecological antioxidant can be prepared using a feasible method resulting in less waste and increased agro-industrial profitability.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app