[Status of zinc and copper in pregnant women and their changes during preeclampsia]

Malek-Mellouli Monia, Ben Amara Fethi, Loussaief-Ben Amara Wafa, Reziga Hédi
Annales de Biologie Clinique 2012, 70 (4): 423-9
In order to evaluate the status of zinc and copper in pregnant women and in preeclampsia, we conducted a prospective case-control study. It involved 56 pregnant women compared with 30 non-pregnant women selected as controls. For pregnant women, serum levels of zinc, copper and ceruloplasmin were determined quarterly. These same measurements were performed once in controls. The comparison of various parameters in normal pregnancy and in control women revealed a statistically significant decrease in serum levels of zinc from 1st to 3rd quarter. The serum levels of copper were normal both in controls and in parturients. However, a significant increase of copper levels from 1st to 3rd quarter of pregnancy was found. The serum levels of ceruloplasmin appear to be invariable during pregnancy. Moreover, we noted a disturbance of these parameters in preeclampsia (hypozincemia, hypocupremia and a significant increase of ceruloplasmin). Zinc and copper are essential for the development and fetal growth. Their involvement in several maternal-fetal complications is not currently in any doubt.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"