JOURNAL ARTICLE
REVIEW

[Kidney and bone update : the 5-year history and future of CKD-MBD. The changes after the introduction of CKD-MBD as a new entity]

Masahiro Koizumi, Masafumi Fukagawa
Clinical Calcium 2012, 22 (7): 969-77
22750928
Recent clinical studies have indicated that mineral metabolism disorder in chronic kidney disease (CKD) is not a disease confined to bone, but a systemic disease that determine the prognosis by promoting vascular calcification. In the context of this paradigm shift, KDIGO (Kidney Disease : Improving Global Outcomes) introduced a new disease entity "CKD-bone and mineral disorder (MBD) " in 2005, and released clinical practice guideline on the management of CKD-MBD in 2009. This guideline is based on strict systemic evidence review and has had considerable effect on clinical practice. However, on the other hand, it became apparent that only a few clinical studies could support the recommendation of this guideline with high-quality evidence. There is a compelling need for accumulation of clinical findings with high-quality evidence.

Full Text Links

Find Full Text Links for this Article

Discussion

You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read
22750928
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"