Add like
Add dislike
Add to saved papers

[Intima-media thickness in obese adolescents and their relation with metabolic syndrome].

INTRODUCTION: Obese adolescents have higher cardiovascular risk (CVR). Intima-media thickness (IMT) detects early arterial vascular compromise.

OBJECTIVE: To evaluate whether obese adolescents have higher vascular compromise measured by IMT than nonobese adolescents, and if this is greater in those with metabolic syndrome (MS).

METHOD: The study group (SG), obese children (BMI/age > p95), with and without MS and control group (CG), non-obese (BMI/age p10-85) and non nutritional or endocrine disease. We measured serum lipids, oral glucose tolerance test with insulin and carotid artery ultrasound. To evaluate the differences between test groups we used parametric and nonparametric statistics.

RESULTS: We evaluated 45 obese adolescents (20 women), 19 with MS, age 13 (9-16) years and 18 controls (14 women), aged 13 (11-16) years. IMT of carotid bulb and internal carotid artery (ICA) were significantly higher in SG than CG (0.54 vs. 0.34, 0.34 vs. 0.25, p < 0.05). There was no difference between obese groups. IMT of ICA and bulb correlated positively with BMIz (r = 0.3 and 0.6, p < 0.05) and with waist circumference (CC) (r = 0.3 and 0.55, p < 0, 05). IMT of ICA was positively correlated with fasting insulin, HOMA and systolic blood pressure. In multivariate analysis only BMI and CC were associated independently to IMT.

CONCLUSION: Obesity is an early risk factor for cardiovascular damage measured by IMT and IMT of ICA demonstrated a higher correlation with cardiovascular risk factors.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app