JOURNAL ARTICLE

Leukoreduction in patients with severe pertussis with hyperleukocytosis

Gonzalo Oñoro, Alberto García Salido, Ignacio Mastro Martínez, Beatriz Cabeza, María Gillén, Amelia Martínez de Azagra
Pediatric Infectious Disease Journal 2012, 31 (8): 873-6
22549439
When pertussis is associated with hyperleukocytosis, mortality approaches to 80%. Immature leukocytes have been identified in pulmonary arterioles, small arteries and venules. Techniques aimed at reducing leukocyte mass might improve the prognosis of these patients. We report our experience with 3 patients in whom a leukoreduction was performed in the context of severe pertussis and hyperleukocytosis.

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