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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Amphiphilic α-helix mimetics based on a benzoylurea scaffold.
Organic & Biomolecular Chemistry 2012 August 15
The design and synthesis of amphiphilic benzoylurea α-helix mimetics is described. These conformationally constrained molecules allow for the correct angular and spatial projection of hydrophobic and hydrophilic groups and thus the reproduction of side-chains on both faces of an α-helix.
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