RAS blockade, hyperkalemia and AKI—look and you will find

Robert D Toto
Nature Reviews. Nephrology 2012, 8 (5): 257-8
Aliskiren combined with other inhibitors of the renin–angiotensin system increases the risk of hyperkalemia. This risk does not translate into an increased incidence of acute kidney injury, suggest the results of a meta-analysis. However, further research is needed to fully evaluate the safety of combination therapy with aliskiren.

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