Vitamin B6 in the treatment of the premenstrual syndrome—a review

J Kleijnen, G Ter Riet, P Knipschild
British Journal of Obstetrics and Gynaecology 1990, 97 (9): 847-52
A search of the literature yielded 12 controlled trials on vitamin B6 in the treatment of the premenstrual syndrome. These are discussed with emphasis on methodological aspects. A major drawback of the trials is the limited number of patients included. The existing evidence of positive effects of vitamin B6 is weak, and some well-designed trials with positive results would be needed to change this view.

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