[Angio-oedema and medication that interferes with the renin-angiotensin-aldosterone system—a systematic review]

Hannah Elena Suhrs, Hans Ibsen
Ugeskrift for Laeger 2012 March 12, 174 (11): 724-9
Angio-oedema is a rare, but potentially life-threatening side effect to medication that interferes with the renin-angiotensin-aldosterone system. Clinically controlled trials were reviewed and the incidence assessed. We conclude, that treatment with an angiotensin receptor blocker can be tried after angiotensin-converting enzyme inhibitor (ACE-I) induced angio-oedema. The assessment should be individually based and take the severity of the previous attack and the weight of the indication into account. The risk on ACE-I might be greater in persons that have had angio-oedema for other reasons.

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