Case Reports
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Research Support, Non-U.S. Gov't
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Esophageal xanthoma--report of two new cases and review of the literature.

BACKGROUND: Esophageal xanthoma is a very rare lesion which can be incidentally discovered during endoscopy. Only eleven cases have been reported, including ours.

CASE REPORTS: We present two new cases of esophageal xanthoma localized in the lower esophagus in a 56-year-old woman and a 62-year-old man. Endoscopically, esophageal xanthoma appears as yellowish granular spots or a slightly elevated lesion. Microscopically, it consists of fat accumulation in foamy histiocytes beneath the squamous epithelium.

CONCLUSIONS: The clinical and pathological importance of these lesions and what they mean in patients is discussed, along with a review of the literature.

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