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Treatment of Kimura disease with intravenous immunoglobulin

Victor Hernandez-Bautista, Marco Antonio Yamazaki-Nakashimada, Ruben Vazquez-García, Daniela Stamatelos-Albarrán, Daniel Carrasco-Daza, Ana Luisa Rodríguez-Lozano
Pediatrics 2011, 128 (6): e1633-5
Kimura disease is an uncommon chronic inflammatory condition of unknown etiology and is characterized by painless subcutaneous nodules, usually affecting the head and neck, eosinophilia, and markedly elevated immunoglobulin E levels. Several reports have described the main modalities of treatment; both corticosteroids and surgery have provided good results, but occasionally corticosteroids cannot be tapered as the disease flares up. We report here the case of an 8-year-old boy diagnosed with Kimura disease who was successfully treated with 1 dose of intravenous immunoglobulin as a steroid-sparing agent.

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