JOURNAL ARTICLE

[Management of acute alcoholic steatohepatitis]

Fabienne Groebli, Laurent Spahr, Nicolas Garin
Revue Médicale Suisse 2011 October 19, 7 (313): 2030, 2032-4
22073699
Alcoholic steatohepatitis is an acute inflammatory liver disorder that often complicates the course of underlying cirrhosis. Severe alcoholic steatohepatitis, defined as a Maddrey's discriminant function greater than 32 or association with hepatic encephalopathy, carries a high short-term mortality that is significantly reduced by corticosteroids. A comprehensive work-up is necessary for the presence of concomitant infection or associated viral hepatitis. A liver biopsy must be performed to confirm the diagnosis prior to initiation of steroids. This article summarizes the management of alcoholic steatohepatitis.

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