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Photodynamic therapy for best disease complicated by choroidal neovascularization in children.

PURPOSE: To describe the results of photodynamic therapy (PDT) with verteporfin for the treatment of choroidal neovascularization (CNV) associated with Best vitelliform macular dystrophy (BVMD) in children.

METHODS: Five eyes of four children diagnosed as having BVMD complicated by CNV received a single session of PDT. Response to treatment was monitored with fluorescein angiography and optical coherence tomography.

RESULTS: All eyes responded well to one session of PDT with significant increases in visual acuity in four of the five eyes. Increase or stabilization of visual acuity was preserved during a mean follow-up period of 25 months.

CONCLUSION: PDT may be an effective treatment for CNV associated with BVMD in children.

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