Letter: Neutrophilic eccrine hidroadenitis with atypical findings

Emiliano Grillo, Sergio Vano-Galvan, Carmen Gonzalez, Jaén Pedro
Dermatology Online Journal 2011 September 15, 17 (9): 14
Neutrophilic eccrine hidradenitis (NEH) was originally described as a distinctive dermatosis occurring in patients undergoing chemotherapy, especially associated with the use of cytarabine in the treatment of acute myelogenous leukemia (AML). This disorder is characterized by a neutrophilic infiltrate around the eccrine glands and coils and is associated with necrosis. However, atypical findings in the histology have been reported. To the best of our knowledge, leukocytoclastic vasculitis has not been described in association with NEH. We hypothesize that a toxic effect of cytarabine may damage the vessel wall to some extent, causing a vasculitic phenomenon.

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