We have located links that may give you full text access.
COMPARATIVE STUDY
JOURNAL ARTICLE
RANDOMIZED CONTROLLED TRIAL
RESEARCH SUPPORT, NON-U.S. GOV'T
Extraction socket preservation graft before implant placement with calcium sulfate hemihydrate and platelet-rich plasma: a clinical and histomorphometric study in humans.
Journal of Periodontology 2012 April
BACKGROUND: The aim of this investigation is to evaluate clinical and histologic outcome of using medical-grade calcium sulfate hemihydrate (MGCSH) mixed with platelet-rich plasma (PRP) for extraction socket preservation graft before implant placement.
METHODS: This study is a single-site, randomized and controlled investigation. Sixteen patients with a non-restorable tooth requiring extraction followed by implant placement were enrolled in this study. After extraction of a tooth, eight selected patients randomly received MGCSH mixed with PRP in the extraction sockets (test group), and eight selected patients randomly received collagen resorbable plug dressing material (control group). At the time of extraction and 3 months later (at implant placement surgery), vertical and horizontal socket dimensions were measured. Bone core samples were retrieved from the center of the healed socket before implant placement for histomorphometric analysis.
RESULTS: There was a statistically significant difference between the two groups based on histomorphometric analysis (P <0.05). New vital bone percentage regenerated after 3 months of healing was 66.5% ± 10.4% in sockets grafted with MGCSH mixed with PRP compared to 38.3% ± 9.3% collagen resorbable plug. There was no statistically significant difference in the amount of vertical and horizontal bone resorption (P >0.05) between groups. In all cases but two in the control group, implants were placed with primary stability.
CONCLUSION: MGCSH mixed with PRP showed greater vital bone volume at 3 months with rapid enhancement of bone healing compared to PRP-free collagen resorbable graft.
METHODS: This study is a single-site, randomized and controlled investigation. Sixteen patients with a non-restorable tooth requiring extraction followed by implant placement were enrolled in this study. After extraction of a tooth, eight selected patients randomly received MGCSH mixed with PRP in the extraction sockets (test group), and eight selected patients randomly received collagen resorbable plug dressing material (control group). At the time of extraction and 3 months later (at implant placement surgery), vertical and horizontal socket dimensions were measured. Bone core samples were retrieved from the center of the healed socket before implant placement for histomorphometric analysis.
RESULTS: There was a statistically significant difference between the two groups based on histomorphometric analysis (P <0.05). New vital bone percentage regenerated after 3 months of healing was 66.5% ± 10.4% in sockets grafted with MGCSH mixed with PRP compared to 38.3% ± 9.3% collagen resorbable plug. There was no statistically significant difference in the amount of vertical and horizontal bone resorption (P >0.05) between groups. In all cases but two in the control group, implants were placed with primary stability.
CONCLUSION: MGCSH mixed with PRP showed greater vital bone volume at 3 months with rapid enhancement of bone healing compared to PRP-free collagen resorbable graft.
Full text links
Related Resources
Trending Papers
Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical Research in Cardiology : Official Journal of the German Cardiac Society 2024 April 12
Proximal versus distal diuretics in congestive heart failure.Nephrology, Dialysis, Transplantation 2024 Februrary 30
World Health Organization and International Consensus Classification of eosinophilic disorders: 2024 update on diagnosis, risk stratification, and management.American Journal of Hematology 2024 March 30
Efficacy and safety of pharmacotherapy in chronic insomnia: A review of clinical guidelines and case reports.Mental Health Clinician 2023 October
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app