46 XX pure gonadal dysgenesis: an infrequent cause of primary amenorrhoea

Salvador Pertusa, Ana Palacios
BMJ Case Reports 2009, 2009
Amenorrhoea can be primary or secondary. Primary amenorrhoea is a relatively common problem among teenage girls. They usually consult their paediatrician or family doctor. This condition is present in patients with normal secondary sexual characteristics but no menarche by 16 years of age, or patients who have not had menstrual flow by age 14 and are lacking normal secondary sexual characteristics. Gonadal dysgenesis is an infrequent cause for primary amenorrhoea. In this paper, the case of a 16-year-old girl whose mother consulted their family doctor because of worries about her daughter's lack of menarche is presented. A blood test showed elevated levels of follicle stimulating hormone (FSH) and luteinising hormone (LH) and low levels of oestradiol. An abdominal ultrasound was abnormal. A diagnostic laparoscopy with biopsy of both gonads was performed. Replacement hormonal therapy was applied resulting in normal menstruations after few months. An early diagnosis is extremely important.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"