[Statins can maybe reduce the risk of venous thromboembolism]

Anne Pernille Toft-Petersen, Reimar Wernich Thomsen, Erik Berg Schmidt, Torben Bjerregaard Larsen
Ugeskrift for Laeger 2011 May 30, 173 (22): 1558-63
Recent reports suggest beneficial effects of statin treatment on risk of venous thromboembolism (VTE). This review studies the existing literature on statins and VTE: one meta-analysis, one randomized controlled trial, four cohort studies and eight case-control studies. The hypothesis of a risk reducing effect of statins on recurrent VTE is supported, but the included studies are heterogeneous; and there is a risk of uncontrolled confounding. Randomized clinical trials aimed at clarifying whether statins can prevent recurrent VTE or not are warranted.


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