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Lobar distribution of cerebral microbleeds: the Rotterdam Scan Study.
Archives of Neurology 2011 May
OBJECTIVE: To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds.
DESIGN: Population-based, cross-sectional analysis.
SETTING: The Rotterdam Scan Study.
PARTICIPANTS: A total of 198 persons (age range, 61-95 years) with lobar microbleeds.
MAIN OUTCOME MEASURES: Distribution of microbleeds over different lobes.
RESULTS: We found that lobar cerebral microbleeds occurred significantly more often in the temporal lobe, a region known to be more affected in cerebral amyloid angiopathy.
CONCLUSION: This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.
DESIGN: Population-based, cross-sectional analysis.
SETTING: The Rotterdam Scan Study.
PARTICIPANTS: A total of 198 persons (age range, 61-95 years) with lobar microbleeds.
MAIN OUTCOME MEASURES: Distribution of microbleeds over different lobes.
RESULTS: We found that lobar cerebral microbleeds occurred significantly more often in the temporal lobe, a region known to be more affected in cerebral amyloid angiopathy.
CONCLUSION: This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.
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