We have located links that may give you full text access.
Journal Article
Research Support, Non-U.S. Gov't
No change in B-type natriuretic peptide levels assessed in the late postoperative period in patients with severe mitral regurgitation after mitral valve surgery.
The impact of mitral valve (MV) surgery on levels of B-type natriuretic peptide (BNP) postoperatively has not been clearly evaluated. The aim of this study was to assess whether BNP levels decrease three to six months after MV surgery in patients with severe mitral regurgitation (MR). We prospectively enrolled patients who were referred for MV surgery with severe MR. BNP levels were measured prior to and after surgery. The mean age was 61.3 ± 13.6 years; 75% were male (n = 52). There was no difference between the mean preoperative and postoperative BNP (242.9 ± 280.3 pg/ml, 290.8 ± 549.8 pg/ml, P = 0.45) obtained at a mean of 138.7 ± 33.5 days with the bias-corrected bootstrapped 95% confidence intervals, 117.6-321.8 pg/ml and 185.4-483.8 pg/ml, respectively. Postoperative BNP tended to increase as the amount of MR increased (no MR: 212.7 ± 197.5 pg/ml, 1+MR: 592.9 ± 1174.9 pg/ml, 2+MR: 133.6 ± 121.6 pg/ml, 3+MR: 547.7 ± 332.0 pg/ml; P < 0.0001). A mild inverse correlation was noted with postoperative BNP and postoperative ejection fraction (r = -0.2596). A decrease in the ejection fraction was noted after surgery (51.7 ± 11.1%, 56.3 ± 9.6%; P = 0.03). Our findings contradict an intuitive thought that BNP levels should decrease after MV surgery for MR.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app