Serial position effects in mild cognitive impairment

Diane B Howieson, Nora Mattek, Adriana M Seeyle, Hiroko H Dodge, Dara Wasserman, Tracy Zitzelberger, Kaye Jeffrey
Journal of Clinical and Experimental Neuropsychology 2011, 33 (3): 292-9
Mild cognitive impairment (MCI) is often associated with the preclinical phase of Alzheimer's disease (AD). Special scoring of word-list recall data for serial position has been suggested to improve discrimination of normal aging from dementia. We examined serial position effects in word-list recall for MCI participants compared to Alzheimer patients and controls. Individuals with MCI, like Alzheimer patients, had a diminished primacy effect in recalling words from a list. No alternative scoring system was better than standard scoring of word-list recall in distinguishing MCI patients from controls. Retention weighted scoring improved the discrimination of MCI and AD groups.

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