AIDS-associated Penicillium marneffei infection of the central nervous system

Thuy Le, Nguyen Huu Chi, Ngo T Kim Cuc, Tran Phu Manh Sieu, Cecilia M Shikuma, Jeremy Farrar, Jeremy N Day
Clinical Infectious Diseases 2010 December 15, 51 (12): 1458-62
Penicillium marneffei is an important human immunodeficiency virus-associated opportunistic infection endemic in Southeast Asia. Central nervous system infection has not been described. We report the first case series of 21 human immunodeficiency virus-infected patients who presented with a syndrome consistent with acute central nervous system infection and who had Penicillium marneffei isolated from cerebrospinal fluid.

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