Evaluation of HL-20 roller pump and Rotaflow centrifugal pump on perfusion quality and gaseous microemboli delivery

Stella Yee, Feng Qiu, Xiaowei Su, Alan Rider, Allen R Kunselman, Yulong Guan, Akif Undar
Artificial Organs 2010, 34 (11): 937-43
The purpose of this study was to compare the HL-20 roller pump (Jostra USA, Austin, TX, USA) and Rotaflow centrifugal pump (Jostra USA) on hemodynamic energy production and gaseous microemboli (GME) delivery in a simulated neonatal cardiopulmonary bypass (CPB) circuit under nonpulsatile perfusion. This study employed a simulated model of the pediatric CPB including a Jostra HL-20 heart-lung machine (or a Rotaflow centrifugal pump), a Capiox BabyRX05 oxygenator (Terumo Corporation, Tokyo, Japan), a Capiox pediatric arterial filter (Terumo Corporation), and ¼-inch tubing. The total volume of the experimental system was 700mL (500mL for the circuit and 200mL for the pseudo neonatal patient). The hematocrit was maintained at 30% using human blood. At the beginning of each trial, a 5mL bolus of air was injected into the venous line. Both GME data and pressure values were recorded at postpump and postoxygenator sites. All the experiments were conducted under nonpulsatile perfusion at three flow rates (500, 750, and 1000mL/min) and three blood temperatures (35, 30, and 25°C). As n=6 for each setup, a total of 108 trials were done. The total number of GME increased as temperature decreased from 35°C to 25°C in the trials using the HL-20 roller pump while the opposite effect occurred when using the Rotaflow centrifugal pump. At a given temperature, total GME counts increased with increasing flow rates for both pumps. Results indicated the Rotaflow centrifugal pump delivered significantly fewer microemboli compared to the HL-20 roller pump, especially under high flow rates. Less than 10% of total microemboli were larger than 40µm in size and the majority of GME were in the 0-20µm class in all trials. Postpump total hemodynamic energy (THE) increased with increasing flow rates and decreasing temperatures in both circuits using these two pumps. The HL-20 roller pump delivered more THE than the Rotaflow centrifugal pump at all tested flow rates and temperature conditions. Results suggest the HL-20 roller pump delivers more GME than the Rotaflow centrifugal pump but produces more hemodynamic energy under nonpulsatile perfusion mode.

Full Text Links

Find Full Text Links for this Article


You are not logged in. Sign Up or Log In to join the discussion.

Related Papers

Remove bar
Read by QxMD icon Read

Save your favorite articles in one place with a free QxMD account.


Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"