JOURNAL ARTICLE

[Hepatic encephalopathy in patients with cirrhosis: new aspects and practical recommendations]

Saskia Ditisheim, Laurent Spahr
Revue Médicale Suisse 2010 September 8, 6 (261): 1667-71
20939401
Hepatic encephalopathy in patients with cirrhosis may present under various clinical aspects, although minimal and episodic forms are the most frequent in clinical practice. Except for the typical alteration of the level of consciousness, other clinical presentations may exist that require additional diagnostic tests and exclusion of other causes. Management of hepatic encephalopathy includes the eviction of the precipitating factor and prevention of recurrence. Medical therapy is mostly directed at the gut as the main source of neurotoxins, but drugs that aimed at correcting liver and brain alterations demonstrate some efficacy. Liver transplantation should be discussed in the presence of persistent symptoms despite optimal medical therapy.

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