[Impact of office hysteroscopy in patients with a history of two or more failed cycles of IVF-ET and pre-ICSI in assisted an reproduction center].

BACKGROUND: Many couples fail to achieve pregnancy instead repeated FIV-TE-ICSI cycles. Good quality embryos for successful pregnancy rates should not be count apart over endometrial receptivity.

OBJECTIVE: To assess the impact of office hysteroscopy in a group of patients with two or more previous failed cycles of FIV-TE-ICSI in an assisted reproduction center.

MATERIAL AND METHOD: Retrospective case control study in patients with problems to conceive in two or more previous failed FIV-TE-ICSI cycles instead good quality embryos and an apparently normal uterine cavity. They were divided in two groups: A with no hysteroscopy perfomed, and 8 with hysteroscopy. Second group was divided in 81 (without pathologic findings) and 82 (with intrauterine abnormalities). Demographic variables were analized, hysteroscopic findings, good quality embryos transferred, biochemical and clinical pregnancies and perinatal results in all groups.

RESULTS: No significant differences were found in demographic variables analyzed among patient with or without office hysteroscopy. Intrauterine abnormalities were found in 16 (64%) patients of group 82. No significant statistical differences were found respect biochemical, clinical pregnancies or live birth new born.

CONCLUSIONS: Instead previous diagnosis of an apparently normal uterine cavity, pathologic abnormalities were found in a significant number of patients. We observed an improvement in pregnancy rates in patients in with HC was realized previous to FIV-TE-ICSI, particularly on those were endometrial pathology was found and corrected, even though the study sample did not allowed to reach results with statistical difference.