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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
Three-component one-pot approach to synthesize benzopyrano[4,3-d]pyrimidines.
Journal of Combinatorial Chemistry 2010 November 9
A novel benzopyrano[4,3-d]pyrimidine scaffold was generated via a three-component one-pot reaction from iodochromone, alkyne, and an amidine through a Sonogashira coupling, condensation, and cycloaddition. This combinatorial synthetic approach provides an efficient, easy construction of a diversified heterocyclic compounds library.
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